"Cain went out from the presence of the Lord, and dwelt in the land of Nod, on the east of Eden" (Genesis 4:16)
The record of Cain, the first child of Adam and Eve, is the record of multitudes of people in every age. He was not interested in God and thus did not want to be where God was.
FIRST - THE CAUSE OF HIS DISINTEREST
The cause of Cain's disinterest in God was sin. It came as a result of his murdering of his brother Abel.
• The event of his sin. This event is recorded in the first part of Genesis 4. It involved a sacrifice. Cain's was without blood. The modernist and apostate who preach a bloodless theology (leave out the necessity of the blood of Christ for the cleansing of sin) persecute those who believe in the necessity of the blood of Christ for the cleansing of sin and so Cain murdered Abel.
• The effect of the sin. Sin does not make us want to be around God. The cause behind the anti-God attitude in our society is sin. You cannot tolerate abortion, homosexualism, gambling, and other sins and still desire to be in God's presence. If you are starting to miss church, your daily devotions etc. you probably have a sin problem.
SECOND - THE CONDUCT OF HIS DISINTEREST
"Cain went out from the presence of the Lord." Cain intentionally moved. He moved away from God. It is true that God is omnipresence and in a sense you can never get away from God.
• The company in Cain's attitude. Cain did not want to be where God was. So Cain will prefer the company of the wicked. Your companions tell us a lot about your interest in God.
• The comparison of his attitude. Cain and Moses were a contrast in their attitude about God's presence. Cain did not want God's presence but Moses did not want to go anywhere without it (Exodus 33:15).
THIRD - THE COUNTRY OF HIS DISINTEREST
"Dwelt in the land of Nod, on the east of Eden." Cain lived in the land of Nod. The word "Nod" means to wander. When you leave the presence of God you will wander. Nod may have popularity, possessions, and position as Cain had in Nod but it is the land of the aimless, the dissatisfied, and the restless.
• The country of dissatisfaction. "Nod" is like the world, it does not satisfy, it is the land of the wandering spirit. "Ever learning, but never able to come to the knowledge of the truth" (II Timothy 3:7). Cain's dissatisfaction is described by Solomon who said he tried everything and found that "All was vanity and vexation of spirit, and there was no profit under the sun" (Ecclesiastes 2:11).
• The country of dishonor. "East of Eden" Eden was where God's honor was. Man was prohibited from entering Eden because man would not honor God's Word. Cain lived apart from Eden because he would not honor God's word.